Impact of hypnosis during embryo transfer on the outcome of in vitro fertilization– embryo transfer: a case-control study

Eliahu Levitas, M.D.,a,b Aldo Parmet, M.D.,b Eitan Lunenfeld, M.D.,a,b Yacov Bentov, M.D.,a,b Eliezer Burstein, M.D.,a,b Michael Friger, Ph.D.,c and Gad Potashnik, M.D.a,b
a-Fertility and IVF Unit, b-Department of Obstetrics and Gynecology, Soroka University Medical Center, and c-Department of
Epidemiology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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Objective: To investigate whether hypnosis during ET contributes to successful IVF/ET outcome.

Design: Case-control clinical study.

Setting: Academic Fertility and IVF Unit, Soroka Medical Center, Beer-Sheva, Israel.

Patient(s): Infertile couples undergoing IVF.

Intervention(s): Ninety-eight IVF/ET cycles with hypnosis during the ET procedure were matched with 96 regular IVF/ET cycles.

Main Outcome Measures: Comparison of clinical pregnancy and implantation rates between the two groups.

Result(s): We obtained 52 clinical pregnancies out of 98 cycles (53.1%) with an implantation rate of 28% among hypnosis IVF/ET cycles, and 29 out of 96 (30.2%) clinical pregnancies and an implantation rate of 14.4% in the control cycles. Our overall IVF program pregnancy rate for the same period was 32.1%. Logistic regression analysis was performed emphasizing the positive contribution of hypnosis to the IVF/ET conception rates.

Conclusion(s): This study suggests that the use of hypnosis during ET may significantly improve the IVF/ET
cycle outcome in terms of increased implantation and clinical pregnancy rates. Furthermore, it seems that the
patients’ attitude to the treatment was more favorable. (Fertil Steril 2006;85:1404 – 8. ©2006 by American
Society for Reproductive Medicine.)

Key Words: IVF/ET, hypnosis, implantation rate, pregnancy rate.

The full article is article is available at:


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